AskDefine | Define kinase

Dictionary Definition

kinase n : an enzyme that catalyzes the conversion of a proenzyme to an active enzyme

User Contributed Dictionary

English

Noun

  1. Any of a group of enzymes that transfers phosphate groups from high-energy donor molecules, such as ATP, to specific target molecules (substrates); the process is termed phosphorylation.

See also

Extensive Definition

In chemistry and biochemistry, a kinase, alternatively known as a phosphotransferase, is a type of enzyme that transfers phosphate groups from high-energy donor molecules, such as ATP, to specific target molecules (substrates); the process is termed phosphorylation (An enzyme that removes phosphate groups from targets is known as a phosphatase.)

Types

The largest group of kinases are protein kinases, which act on and modify the activity of specific proteins. These are used extensively to transmit signals and control complex processes in cells. Up to 518 different kinases have been identified in humans. Their enormous diversity and role in signaling makes them attractive targets for drug design.
Various other kinases act on small molecules (lipids, carbohydrates, amino acids, nucleotides, and more), either for signaling or to prime them for biochemical reactions in metabolism. These are named after their substrates.
kinase in Czech: Kinasa
kinase in German: Kinasen
kinase in Spanish: Quinasa
kinase in French: Kinase
kinase in Italian: Chinasi
kinase in Hebrew: קינאז
kinase in Dutch: Kinase
kinase in Japanese: キナーゼ
kinase in Occitan (post 1500): Quinasa
kinase in Polish: Kinazy
kinase in Portuguese: Cinase
kinase in Russian: Киназы
kinase in Finnish: Kinaasi
kinase in Swedish: Kinas
kinase in Chinese: 激酶
Privacy Policy, About Us, Terms and Conditions, Contact Us
Permission is granted to copy, distribute and/or modify this document under the terms of the GNU Free Documentation License, Version 1.2
Material from Wikipedia, Wiktionary, Dict
Valid HTML 4.01 Strict, Valid CSS Level 2.1